| Legacy Healthcare Services Inc | Greenville | 3,223 |
| Prisma Health University Medical Group | Greenville | 2,493 |
| University Medical Associates of the Medical University of South Carol | Charleston | 1,668 |
| Spartanburg Medical Center | Spartanburg | 1,078 |
| Prisma Health Medical Group-Midlands | Columbia | 1,068 |
| Lexington Health Inc | West Columbia | 904 |
| McLeod Physician Associates II | Little River | 550 |
| Roper Saint Francis Physicians Network | N Charleston | 528 |
| SC House Calls Inc | West Columbia | 432 |
| Acs Primary Care Physicians - Southeast PC | Myrtle Beach | 420 |
| McLeod Regional Medical Center of the Pee Dee Inc | Myrtle Beach | 406 |
| Self Medical Group | Greenwood | 395 |
| Anmed Health | Anderson | 344 |
| Southeastern Hospitalist Services PC | Myrtle Beach | 297 |
| Bon Secours Medical Group Greenville Specialty Care LLC | Greenville | 292 |
| Fox Rehabilitation Services of South Carolina, LLC | Lexington | 291 |
| Cora South Carolina LLC | Bluffton | 236 |
| Curana Health of South Carolina PC | Summerville | 231 |
| Ch Specialty Services SC LLC | North Charleston | 230 |
| Greenville Proaxis Therapy LLC | Greenville | 224 |
| South Carolina Dept of Mental Health Accounting Office | Bennettsville | 221 |
| Medical University Hospital Authority | Lake City | 220 |
| Georgetown Physician Associates, LLC | Myrtle Beach | 214 |
| Bon Secours St Francis Xavier Hospital Inc | Charleston | 207 |
| Charleston Counseling Center PC | Mount Pleasant | 203 |
| Beaufort County Memorial Hospital | Beaufort | 194 |
| Charlotte Eye Ear Nose and Throat Associates PA | Rock Hill | 182 |
| Self Regional Healthcare | Laurens | 180 |
| Lifesource of North Carolina | Clinton | 178 |
| Novant Health Urgent Cares LLC | Aiken | 177 |
| Prisma Health Urgent Care of South Carolina PC | Columbia | 169 |
| Wound Management Specialists LLC | Columbia | 149 |
| Palmetto Primary Care Physicians LLC | Saint George | 144 |
| 24 on Physicians of SC LLC | Charleston | 141 |
| Benchmark Healthcare Services LLC | Hanahan | 137 |
| East Cooper Physician Group LLC | Mount Pleasant | 136 |
| Pelham Medical Center | Greer | 134 |
| Conway Hospital Inc | Conway | 127 |
| Trident Anesthesia Group LLC | Charleston | 119 |
| Minuteclinic Diagnostic South Carolina LLC | Columbia | 113 |
| Hilton Head Regional Physician Group LLC | Bluffton | 113 |
| Palmetto Anesthesia Associates | Greenville | 109 |
| St Francis Physician Services Inc | Greenville | 102 |
| Rsfh - Ati Physical Therapy LLC | Summerville | 101 |
| Health Providers of America LLC | Greenville | 99 |
| Beach Anesthesia, LLC | Columbia | 97 |
| Orthosc LLC | Myrtle Beach | 91 |
| Piedmont Physician Network LLC | Fort Mill | 89 |
| Georgetown Memorial Hospital | Georgetown | 88 |
| The Weston Group of South Carolina Inc | Conway | 82 |
| Carolina Family Care Inc | Summerville | 81 |
| Lowcountry Urgent Care LLC | Walterboro | 81 |
| Charleston Carenow Urgent Care LLC | North Charleston | 80 |
| Hartsville Medical Group LLC | Hartsville | 80 |
| Collective Therapy Corp | Fort Mill | 79 |
| Charleston ENT Associates, LLC | Charleston | 78 |
| Hopehealth, Inc. | Florence | 77 |
| Apogee Medical Group South Carolina | Columbia | 74 |
| Broad River Physicians Group, LLC | Charleston | 71 |
| Skin Surgery Center PA | Mount Pleasant | 70 |
| Atlantic Coast Anesthesia Services PC | Myrtle Beach | 68 |
| Caresouth Carolina Inc. | Bennettsville | 67 |
| Carolina Orthopaedic and Neurosurgical Associates | Spartanburg | 67 |
| Medcare Express - North Charleston LLC | Summerville | 66 |
| Eye Care Associates of SC LLC | Mount Pleasant | 65 |
| Roper Hospital Inc | Charleston | 65 |
| Carolina Radiology Associates LLC | Myrtle Beach | 64 |
| Waccamaw Community Hospital | Murrells Inlet | 64 |
| Optimum Anesthesia | Okatie | 64 |
| Anesthesia Associates of Rock Hill PA | Rock Hill | 62 |
| Low Country Anesthesia, PA | Beaufort | 62 |
| Colonial Family Practice LLC | Sumter | 62 |
| McLeod Loris Seacoast Hospital | Myrtle Beach | 61 |
| McLeod Health Clarendon | Timmonsville | 60 |
| Palmetto Infusion Services LLC | Charleston | 60 |
| Bon Secours Ambulatory Services - St. Francis, LLC | Greenville | 57 |
| Gastroenterology Associates, PA | Clemson | 57 |
| Grand Strand Surgical Specialists LLC | Myrtle Beach | 57 |
| Aiken Professional Association LLC | Graniteville | 55 |
| Strand Physician Specialists PA | Myrtle Beach | 55 |
| Sound Physicians Emergency Medicine of South Carolina LLC | Aiken | 54 |
| Excel Rehabilitation and Sports | Greenville | 53 |
| Lifesource Prime Inc | Clinton | 53 |
| Clemson Eye PA | Sumter | 52 |
| Elite Integrated Therapy Centers LLC | Greenville | 51 |
| Tidelands Anesthesia Group LLC | Murrells Inlet | 51 |
| Charleston Gastroenterology Specialists | Charleston | 49 |
| Coastal Carolina Multispecialty Associates LLC | Walterboro | 49 |
| Musc Affiliate Physicians | Greer | 48 |
| Stedfast Medical Services LLC | Columbia | 47 |
| Instride Foot and Ankle Specialists, PLLC | Lancaster | 46 |
| Centerwell Senior Primary Care SC PC | Greenville | 45 |
| Drayer Physical Therapy-South Carolina ,LLC | Columbia | 45 |
| Abbeville County Memorial Hospital | Abbeville | 45 |
| Liberty Doctors LLC | Goose Creek | 44 |
| Beaufort Orthopaedic Sports and Spine Center LLC | Hilton Head Island | 44 |
| Oceanic Counseling Group LLC | Myrtle Beach | 44 |
| Eau Claire Cooperative Health Center, Inc. | Columbia | 43 |
| Ivyrehab Focus, Inc. | Lake Wylie | 43 |
| South Carolina Sports Medicine and Orthopaedic Center | North Charleston | 43 |