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Isaac Edward Alwine, M.D.

NPI 1619364668ActiveIndividual· Internal Medicine, Hematology & Oncology· Spartanburg, SC

Internal Medicine, Hematology & Oncology (M.D.) with Spartanburg Medical Center, practicing in Spartanburg, South Carolina. Their prescriptions cost Medicare Part D more than their services did: $2,180,081 for 2,757 claims, against $117,484 paid for services in 2024. Pfizer Inc. was the largest of 15 companies reporting payments in 2025, $871.57 in all, mostly food and beverage. Lists Cherokee Medical Center and 2 other hospitals as hospital affiliations.

Overview

NPI1619364668
StatusActive
Entity typeIndividual
CredentialM.D.
Sole proprietorYes
NPI issuedApr 16, 2015
Last updated in NPPESAug 4, 2021
Certified by providerAug 4, 2021

Specialties and licenses

About license numbers in NPPES

Exclusion screening

ListResultDetails
HHS-OIG LEIE · Oct 9, 2026No matchChecked by NPI and by name + state
North Carolina Medicaid · Nov 4, 2026No match—
New York OMIG · Nov 4, 2026No match—
Ohio Medicaid · Nov 4, 2026No match—
Pennsylvania Medicheck · Nov 4, 2026No match—
Washington HCA · Nov 4, 2026No match—

Official OIG search · How matching works ·Bulk check a roster

Medicare

Enrollment (PECOS)Enrolled Practitioner - Hematology (SC)
Accepts assignmentYes (participating)

Medicare services in 2024

Medicare patients566
Services billed1,620 across 12 procedure codes
Paid by Medicare$117,484

Part D prescriptions in 2024

Prescriptions (claims)2,757 · 4,267 30-day fills
Patients467
Total drug cost$2,180,081
Generic share92% of claims

Medicare sources and data years

Education and affiliations

Graduation year2015
Medicare specialtyHematology
Secondary specialtiesMedical Oncology

Medical group

Hospital affiliations

Source: CMS Care Compare

Industry payments (Open Payments)

  • 2025$871.57 · 41 payments from 15 companies
  • 2024$622.56 · 27 payments from 10 companies

Top paying companies in 2025

What the 2025 payments were for

  • Food and Beverage$845.24 · 40 payments
  • Education$26.33 · 1 payment

Receiving payments does not imply wrongdoing. What Open Payments covers ·original records

Other Internal Medicine, Hematology & Oncology providers in Spartanburg

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