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John Charles Isaac, M.D.

NPI 1295799005ActiveIndividual· Internal Medicine, Interventional Cardiology· Houston, TX

Internal Medicine, Interventional Cardiology (M.D.) in Houston, Texas, trained at University of Texas Southwestern Medical School at Dallas (class of 1994). Their prescriptions cost Medicare Part D more than their services did: $4,823,673 for 18,588 claims, against $1,788,203 paid for services in 2024. Amgen Inc. was the largest of 27 companies reporting payments in 2025, $214,376 in all, mostly speaking and faculty fees.

Overview

NPI1295799005
StatusActive
Entity typeIndividual
CredentialM.D.
Sole proprietorNo
NPI issuedApr 17, 2006
Last updated in NPPESOct 25, 2016

Specialties and licenses

About license numbers in NPPES

Exclusion screening

ListResultDetails
HHS-OIG LEIE · Oct 9, 2026No matchChecked by NPI and by name + state
North Carolina Medicaid · Nov 4, 2026No match—
New York OMIG · Nov 4, 2026No match—
Ohio Medicaid · Nov 4, 2026No match—
Pennsylvania Medicheck · Nov 4, 2026No match—
Washington HCA · Nov 4, 2026No match—

Official OIG search · How matching works ·Bulk check a roster

Medicare

Enrollment (PECOS)Enrolled Practitioner - Cardiovascular Disease (Cardiology) (TX)
Accepts assignmentYes (participating)

Medicare services in 2024

Medicare patients1,253
Services billed9,530 across 73 procedure codes
Paid by Medicare$1,788,203

Part D prescriptions in 2024

Prescriptions (claims)18,588 · 49,179 30-day fills
Patients1,569
Total drug cost$4,823,673
Generic share76% of claims

Medicare sources and data years

Education and affiliations

Medical schoolUniversity of Texas Southwestern Medical School at Dallas
Graduation year1994
Medicare specialtyCardiovascular Disease (Cardiology)
TelehealthOffers telehealth

Medical group

Hospital affiliations

Other facilities

Source: CMS Care Compare

Industry payments (Open Payments)

  • 2025$214,376 · 383 payments from 27 companies
  • 2024$199,612 · 423 payments from 30 companies

Top paying companies in 2025

CompanyAmountPayments
Amgen Inc.$127,762185
Regeneron Healthcare Solutions, Inc.$21,21238
E.R. Squibb & Sons, L.L.C.$20,13527
Heartflow, Inc.$19,53023
Lilly USA, LLC$13,96514

What the 2025 payments were for

  • Compensation for services other than consulting, including serving as faculty or as a speaker at a venue other than a continuing education program$171,043 · 77 payments
  • Travel and Lodging$19,031 · 127 payments
  • Consulting Fee$15,908 · 3 payments
  • Food and Beverage$8,374 · 175 payments
  • Education$20.22 · 1 payment

Receiving payments does not imply wrongdoing. What Open Payments covers ·original records

Other Internal Medicine, Interventional Cardiology providers in Houston

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